CATH Domain 5i3dA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.80	Glycosidases

Domain Context

CATH Clusters

Superfamily	Glycosidases
Functional Family

Enzyme Information

3.2.1.23

Beta-galactosidase.

based on mapping to UniProt P22498

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides.

-!- Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108).

UniProtKB Entries (1)

P22498

BGAL_SACS2

Saccharolobus solfataricus P2

Beta-galactosidase

PDB Structure

PDB	5I3D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase. Iglesias-Fernandez, J., Hancock, S.M., Lee, S.S., Khan, M., Kirkpatrick, J., Oldham, N.J., McAuley, K., Fordham-Skelton, A., Rovira, C., Davis, B.G. Nat. Chem. Biol.