CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.210 | Beta Polymerase; domain 3 |
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3.30.210.10 | DNA polymerase, thumb domain |
Domain Context
CATH Clusters
Superfamily | DNA polymerase, thumb domain |
Functional Family | Repair DNA polymerase X |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P42494
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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UniProtKB Entries (1)
P42494 |
DPOLX_ASFB7
African swine fever virus BA71V
Repair DNA polymerase X
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PDB Structure
PDB | 5HRD |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
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