CATH Domain 5hjsA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

NR1H3_HUMAN

Homo sapiens

Oxysterols receptor LXR-alpha

PDB Structure

PDB	5HJS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and in Vivo Evaluation of Liver X Receptor beta-Selective Agonists for the Potential Treatment of Alzheimer's Disease. Stachel, S.J., Zerbinatti, C., Rudd, M.T., Cosden, M., Suon, S., Nanda, K.K., Wessner, K., DiMuzio, J., Maxwell, J., Wu, Z., Uslaner, J.M., Michener, M.S., Szczerba, P., Brnardic, E., Rada, V., Kim, Y., Meissner, R., Wuelfing, P., Yuan, Y., Ballard, J., Holahan, M., Klein, D.J., Lu, J., Fradera, X., Parthasarathy, G., Uebele, V.N., Chen, Z., Li, Y., Li, J., Cooke, A.J., Bennett, D.J., Bilodeau, M.T., Renger, J. J.Med.Chem.