CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.410 | Factor Xa Inhibitor |
|
4.10.410.10 | Pancreatic trypsin inhibitor Kunitz domain |
Domain Context
CATH Clusters
| Superfamily | Pancreatic trypsin inhibitor Kunitz domain |
| Functional Family | Serine peptidase inhibitor, Kunitz type 1 |
Enzyme Information
UniProtKB Entries (1)
| O43278 |
SPIT1_HUMAN
Homo sapiens
Kunitz-type protease inhibitor 1
|
PDB Structure
| PDB | 5H7V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition
J. Biol. Chem.
|