CATH Domain 5h34B00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.50	OB fold (Dihydrolipoamide Acetyltransferase, E2P)
	2.40.50.140	Nucleic acid-binding proteins

Domain Context

CATH Clusters

Superfamily	Nucleic acid-binding proteins
Functional Family	Methionine--tRNA ligase

Enzyme Information

6.1.1.10

Methionine--tRNA ligase.

based on mapping to UniProt Q74MZ1

ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).

-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.

UniProtKB Entries (1)

Q74MZ1

SYM_NANEQ

Nanoarchaeum equitans Kin4-M

Methionine--tRNA ligase

PDB Structure

PDB	5H34
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Binding Properties of Split tRNA to the C-terminal Domain of Methionyl-tRNA Synthetase of Nanoarchaeum equitans. Suzuki, H., Kaneko, A., Yamamoto, T., Nambo, M., Hirasawa, I., Umehara, T., Yoshida, H., Park, S.Y., Tamura, K. J. Mol. Evol.