CATH Domain 5h17A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	Polycomb protein eed

Enzyme Information

UniProtKB Entries (1)

EZH2_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase EZH2

PDB Structure

PDB	5H17
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED Li, L., Zhang, H., Zhang, M., Zhao, M., Feng, L., Luo, X., Gao, Z., Huang, Y., Ardayfio, O., Zhang, J.H., Lin, Y., Fan, H., Mi, Y., Li, G., Liu, L., Feng, L., Luo, F., Teng, L., Qi, W., Ottl, J., Lingel, A., Bussiere, D.E., Yu, Z., Atadja, P., Lu, C., Li, E., Gu, J., Zhao, K. PLoS ONE