CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.30 | SH3 type barrels. | |
2.30.30.490 | Bromo adjacent homology (BAH) domain |
Domain Context
CATH Clusters
Superfamily | 2.30.30.490 |
Functional Family | DNA (cytosine-5)-methyltransferase |
Enzyme Information
2.1.1.37 |
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P13864
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.
|
UniProtKB Entries (1)
P13864 |
DNMT1_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 1
|
PDB Structure
PDB | 5GUV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem. Biol.
|