CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP kinase, C-terminal domain
Functional Family Diphosphomevalonate decarboxylase

Enzyme Information

4.1.1.33
Diphosphomevalonate decarboxylase.
based on mapping to UniProt Q97UL5
ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO(2).

UniProtKB Entries (1)

Q97UL5
DMD_SACS2
Saccharolobus solfataricus P2
Diphosphomevalonate decarboxylase

PDB Structure

PDB 5GME
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase
Motoyama, K., Unno, H., Hattori, A., Takaoka, T., Ishikita, H., Kawaide, H., Yoshimura, T., Hemmi, H.
J. Biol. Chem.
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