CATH Classification
Level | CATH Code | Description |
---|---|---|
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1 | Mainly Alpha |
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1.20 | Up-down Bundle |
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1.20.200 | Fumarase C; Chain A, domain 2 |
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1.20.200.10 | Fumarase/aspartase (Central domain) |
Domain Context
CATH Clusters
Superfamily | Fumarase/aspartase (Central domain) |
Functional Family | Fumarate hydratase, mitochondrial |
Enzyme Information
4.2.1.2 |
Fumarate hydratase.
based on mapping to UniProt P9WN92
(S)-malate = fumarate + H(2)O.
|
UniProtKB Entries (1)
P9WN92 |
FUMC_MYCTO
Mycobacterium tuberculosis CDC1551
Fumarate hydratase class II
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PDB Structure
PDB | 5F92 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Proc.Natl.Acad.Sci.USA
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