CATH Domain 5f5eA00

Superfamily	SET domain
Functional Family

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q03164

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

KMT2A_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase 2A

PDB	5F5E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for activity regulation of MLL family methyltransferases. Li, Y., Han, J., Zhang, Y., Cao, F., Liu, Z., Li, S., Wu, J., Hu, C., Wang, Y., Shuai, J., Chen, J., Cao, L., Li, D., Shi, P., Tian, C., Zhang, J., Dou, Y., Li, G., Chen, Y., Lei, M. Nature