CATH Domain 5etrA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.560	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK

Domain Context

CATH Clusters

Superfamily	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q2G0Q5_STAA8

Staphylococcus aureus subsp. aureus NCTC 8325

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

PDB Structure

PDB	5ETR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. Dennis, M.L., Pitcher, N.P., Lee, M.D., DeBono, A.J., Wang, Z.C., Harjani, J.R., Rahmani, R., Cleary, B., Peat, T.S., Baell, J.B., Swarbrick, J.D. J.Med.Chem.