CATH Classification
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 |
| Functional Family | Phosphatidylinositol 3-kinase catalytic subunit type 3 |
Enzyme Information
| 2.7.1.137 |
Phosphatidylinositol 3-kinase.
based on mapping to UniProt Q8NEB9
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 3-phosphate.
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UniProtKB Entries (1)
| Q8NEB9 |
PK3C3_HUMAN
Homo sapiens
Phosphatidylinositol 3-kinase catalytic subunit type 3
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PDB Structure
| PDB | 5ENN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent, selective, and orally bioavailable inhibitors of VPS34 provide chemical tools to modulate autophagy in vivo
To Be Published
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