CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.240 | Tyrosyl-Transfer RNA Synthetase |
|
1.10.240.10 | Tyrosyl-Transfer RNA Synthetase |
Domain Context
CATH Clusters
| Superfamily | Tyrosyl-Transfer RNA Synthetase |
| Functional Family | Tryptophan--tRNA ligase |
Enzyme Information
| 6.1.1.2 |
Tryptophan--tRNA ligase.
based on mapping to UniProt Q9UGM6
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).
|
UniProtKB Entries (1)
| Q9UGM6 |
SYWM_HUMAN
Homo sapiens
Tryptophan--tRNA ligase, mitochondrial
|
PDB Structure
| PDB | 5EKD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Binding of Mg2+ATP Enhances Inhibition of Human Mitochondrial Tryptophanyl-tRNA Synthetase by Indolmycin
To Be Published
|