CATH Domain 5e10A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.10	Trypsin Inhibitor V; Chain A
	3.30.10.20

Domain Context

CATH Clusters

Superfamily	3.30.10.20
Functional Family	Transmembrane serine/threonine-protein kinase B

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt P9WI81

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P9WI81

PKNB_MYCTU

Mycobacterium tuberculosis H37Rv

Serine/threonine-protein kinase PknB

PDB Structure

PDB	5E10
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. Prigozhin, D.M., Papavinasasundaram, K.G., Baer, C.E., Murphy, K.C., Moskaleva, A., Chen, T.Y., Alber, T., Sassetti, C.M. J.Biol.Chem.