CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Cell death-related nuclease 4 |
Enzyme Information
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt Q10905
|
UniProtKB Entries (1)
| Q10905 |
CRN4_CAEEL
Caenorhabditis elegans
Cell death-related nuclease 4
|
PDB Structure
| PDB | 5DK5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem.
|