CATH Domain 5daaB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.470	D-amino Acid Aminotransferase; Chain A, domain 1
	3.30.470.10	Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain

Domain Context

CATH Clusters

Superfamily	3.30.470.10
Functional Family	D-alanine aminotransferase

Enzyme Information

2.6.1.21

D-amino-acid transaminase.

based on mapping to UniProt P19938

D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.

-!- The enzyme from thermophilic Bacillus species acts on many D-amino acids with D-alanine and D-2-aminobutyrate as the best amino donors. -!- It can similarly use any of several 2-oxo acids as amino acceptor, with 2-oxoglutarate and 2-oxobutyrate among the best. -!- The enzyme from some other sources has a broader specificity. -!- Formerly EC 2.6.1.10.

UniProtKB Entries (1)

P19938

DAAA_BACYM

Bacillus sp. YM-1

D-alanine aminotransferase

PDB Structure

PDB	5DAA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Effects of the E177K mutation in D-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity. van Ophem, P.W., Peisach, D., Erickson, S.D., Soda, K., Ringe, D., Manning, J.M. Biochemistry