CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.390 | Collagenase (Catalytic Domain) | |
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
Superfamily | Collagenase (Catalytic Domain) |
Functional Family | Serralysin |
Enzyme Information
3.4.24.40 |
Serralysin.
based on mapping to UniProt P23694
Preferential cleavage of bonds with hydrophobic residues in P1'.
-!- An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi. -!- There is broad specificity in cleavage of the insulin B chain, with some species variations. -!- The pH optimum for digesting various proteins is about 9-10. -!- Belongs to peptidase family M10A. -!- Formerly EC 3.4.24.4.
|
UniProtKB Entries (1)
P23694 |
PRZN_SERMA
Serratia marcescens
Serralysin
|
PDB Structure
PDB | 5D7W |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of a thermostable serralysin from Serratia sp. FS14 at 1.1 angstrom resolution.
Acta Crystallogr.,Sect.F
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