CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family Serralysin

Enzyme Information

3.4.24.40
Serralysin.
based on mapping to UniProt P23694
Preferential cleavage of bonds with hydrophobic residues in P1'.
-!- An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi. -!- There is broad specificity in cleavage of the insulin B chain, with some species variations. -!- The pH optimum for digesting various proteins is about 9-10. -!- Belongs to peptidase family M10A. -!- Formerly EC 3.4.24.4.

UniProtKB Entries (1)

P23694
PRZN_SERMA
Serratia marcescens
Serralysin

PDB Structure

PDB 5D7W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a thermostable serralysin from Serratia sp. FS14 at 1.1 angstrom resolution.
Wu, D., Ran, T., Wang, W., Xu, D.
Acta Crystallogr.,Sect.F