CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.840 | Son of Sevenless (SoS) protein; Chain S, domain 2 |
|
1.10.840.10 | Ras guanine-nucleotide exchange factors catalytic domain |
Domain Context
CATH Clusters
| Superfamily | Ras guanine-nucleotide exchange factors catalytic domain |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| Q61193 |
RGL2_MOUSE
Mus musculus
Ral guanine nucleotide dissociation stimulator-like 2
|
| P48555 |
RALA_DROME
Drosophila melanogaster
Ras-related protein Ral-a
|
PDB Structure
| PDB | 5CM9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of the Guanine Nucleotide Exchange Factor Rlf in complex with the small G-protein Ral identifies conformational intermediates of the exchange reaction and the basis for the selectivity.
J.Struct.Biol.
|
