CATH Domain 5c5sA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.555	Phosphatidylinositol 3-kinase; Chain A
	1.10.555.10	Rho GTPase activation protein

Domain Context

CATH Clusters

Superfamily	Rho GTPase activation protein
Functional Family	unconventional myosin-IXa isoform X1

Enzyme Information

UniProtKB Entries (1)

MYO9B_HUMAN

Homo sapiens

Unconventional myosin-IXb

PDB Structure

PDB	5C5S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression Kong, R., Yi, F., Wen, P., Liu, J., Chen, X., Ren, J., Li, X., Shang, Y., Nie, Y., Wu, K., Fan, D., Zhu, L., Feng, W., Wu, J.Y. J.Clin.Invest.