CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.940 | Eukaryotic RPB6 RNA polymerase subunit |
|
3.90.940.10 | RNA polymerase subunit, RPB6/omega |
Domain Context
CATH Clusters
| Superfamily | 3.90.940.10 |
| Functional Family | DNA-directed RNA polymerase subunit omega |
Enzyme Information
| 2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt P0A800
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (2)
| P0A8V2 |
RPOB_ECOLI
Escherichia coli K-12
DNA-directed RNA polymerase subunit beta
|
| R4YEY9 |
R4YEY9_KLEPR
Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
RNA polymerase sigma-54 factor
|
PDB Structure
| PDB | 5BYH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
TRANSCRIPTION. Structures of the RNA polymerase-sigma 54 reveal new and conserved regulatory strategies.
Science
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