CATH Domain 5apjA00

Superfamily	Retinoid X Receptor
Functional Family	Nuclear orphan receptor ROR-beta

RORG_HUMAN

Homo sapiens

Nuclear receptor ROR-gamma

PDB	5APJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma. Olsson, R.I., Xue, Y., von Berg, S., Aagaard, A., McPheat, J., Hansson, E.L., Bernstrom, J., Hansson, P., Jirholt, J., Grindebacke, H., Leffler, A., Chen, R., Xiong, Y., Ge, H., Hansson, T.G., Narjes, F. ChemMedChem