CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt O59952
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (1)

O59952
LIP_THELA
Thermomyces lanuginosus
Lipase

PDB Structure

PDB 5AP9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function.
Skjold-Jrgensen, J., Vind, J., Moroz, O.V., Blagova, E., Bhatia, V.K., Svendsen, A., Wilson, K.S., Bjerrum, M.J.
Biochim. Biophys. Acta