CATH Domain 5ae3A01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.43	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2
	3.30.43.10	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

Superfamily	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family	Alkylglycerone-phosphate synthase

2.5.1.26

Alkylglycerone-phosphate synthase.

based on mapping to UniProt P97275

1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.

-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.

ADAS_CAVPO

Cavia porcellus

Alkyldihydroxyacetonephosphate synthase, peroxisomal

PDB	5AE3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents. Piano, V., Benjamin, D.I., Valente, S., Nenci, S., Marrocco, B., Mai, A., Aliverti, A., Nomura, D.K., Mattevi, A. Acs Chem.Biol.