CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.920 | Histone Acetyltransferase; Chain A |
|
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
| Superfamily | Bromodomain-like |
| Functional Family | ATPase family AAA domain-containing protein 2 |
Enzyme Information
| 3.6.1.3 |
Adenosinetriphosphatase.
based on mapping to UniProt Q6PL18
ATP + H(2)O = ADP + phosphate.
-!- Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39. -!- The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA. -!- Formerly EC 3.6.1.4.
|
UniProtKB Entries (1)
| Q6PL18 |
ATAD2_HUMAN
Homo sapiens
ATPase family AAA domain-containing protein 2
|
PDB Structure
| PDB | 5A5N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors.
J.Med.Chem.
|