1 keywords

CATH Domain 5a3pA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.650 Cupin

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Putative lysine-specific demethylase 5b

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q9UGL1

UniProtKB Entries (1)

Q9UGL1
KDM5B_HUMAN
Homo sapiens
Lysine-specific demethylase 5B

PDB Structure

PDB 5A3P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Johansson, C., Velupillai, S., Tumber, A., Szykowska, A., Hookway, E.S., Nowak, R.P., Strain-Damerell, C., Gileadi, C., Philpott, M., Burgess-Brown, N., Wu, N., Kopec, J., Nuzzi, A., Steuber, H., Egner, U., Badock, V., Munro, S., Lathangue, N.B., Westaway, S., Brown, J., Athanasou, N., Prinjha, R., Brennan, P.E., Oppermann, U.
Nat.Chem.Biol.