CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.50 | Zincin-like fold |
|
1.25.50.10 | Peptidase M1, alanyl aminopeptidase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Peptidase M1, alanyl aminopeptidase, C-terminal domain |
| Functional Family | M1 family aminopeptidase |
Enzyme Information
| 3.4.11.- |
Aminopeptidases.
based on mapping to UniProt O96935
|
UniProtKB Entries (1)
| O96935 |
AMP1_PLAFQ
Plasmodium falciparum FcB1/Columbia
M1 family aminopeptidase
|
PDB Structure
| PDB | 4ZX5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem.
|