CATH Domain 4znzA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1050	Beta-carbonic Anhydrase; Chain A
	3.40.1050.10	Carbonic anhydrase

Domain Context

CATH Clusters

Superfamily	Carbonic anhydrase
Functional Family	Carbonic anhydrase

Enzyme Information

4.2.1.1

Carbonic anhydrase.

based on mapping to UniProt A0A140NBR3

H(2)CO(3) = CO(2) + H(2)O.

-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

A0A140NBR3

A0A140NBR3_ECOBD

Escherichia coli BL21(DE3)

Carbonic anhydrase

PDB Structure

PDB	4ZNZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Protein purification and crystallization artifacts: The tale usually not told. Niedzialkowska, E., Gasiorowska, O., Handing, K.B., Majorek, K.A., Porebski, P.J., Shabalin, I.G., Zasadzinska, E., Cymborowski, M., Minor, W. Protein Sci.