CATH Domain 4zh4F04

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	RNA polymerase sigma factor SigA

Enzyme Information

UniProtKB Entries (1)

RPOA_ECOLI

Escherichia coli K-12

DNA-directed RNA polymerase subunit alpha

PDB Structure

PDB	4ZH4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Feng, Y., Degen, D., Wang, X., Gigliotti, M., Liu, S., Zhang, Y., Das, D., Michalchuk, T., Ebright, Y.W., Talaue, M., Connell, N., Ebright, R.H. Structure