CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family 14-alpha sterol demethylase

Enzyme Information

UniProtKB Entries (1)

A6ZSR0
A6ZSR0_YEAS7
Saccharomyces cerevisiae YJM789
Lanosterol 14-alpha demethylase

PDB Structure

PDB 4ZE2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase.
Sagatova, A.A., Keniya, M.V., Wilson, R.K., Sabherwal, M., Tyndall, J.D., Monk, B.C.
Sci Rep