CATH Classification

Domain Context

CATH Clusters

Superfamily Laminin
Functional Family Coagulation factor VII

Enzyme Information

3.4.21.22
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P00740
FA9_HUMAN
Homo sapiens
Coagulation factor IX

PDB Structure

PDB 4ZAE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of a novel class of potent and selective FIXa inhibitors.
Zhang, T., Andre, P., Bateman, T.J., Chen, Y.H., Desai, K., Ellsworth, K., Geissler, W.M., Guo, L., Hruza, A., Jian, T., Meng, D., Parker, D.L., Qian, X., Reichert, P., Sherer, E.C., Shu, M., Smith, C.J., Sonatore, L.M., Tschirret-Guth, R., Nolting, A.F., Orr, R., Campeau, L.C., Araki, K., Nishimura, T., Sakurada, I., Wood, H.B.
Bioorg.Med.Chem.Lett.
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