CATH Classification
Level | CATH Code | Description |
---|---|---|
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2 | Mainly Beta |
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2.40 | Beta Barrel |
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2.40.10 | Thrombin, subunit H |
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2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
Superfamily | Trypsin-like serine proteases |
Functional Family | Coagulation factor X |
Enzyme Information
3.4.21.22 |
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.
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UniProtKB Entries (1)
P00740 |
FA9_HUMAN
Homo sapiens
Coagulation factor IX
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PDB Structure
PDB | 4YZU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Rapid development of two factor IXa inhibitors from hit to lead.
Bioorg.Med.Chem.Lett.
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