CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family MTA/SAH nucleosidase family protein

Enzyme Information

3.2.2.9
Adenosylhomocysteine nucleosidase.
based on mapping to UniProt P0AF12
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.

UniProtKB Entries (1)

P0AF12
MTNN_ECOLI
Escherichia coli K-12
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

PDB Structure

PDB 4YML
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Tight binding enantiomers of pre-clinical drug candidates.
Evans, G.B., Cameron, S.A., Luxenburger, A., Guan, R., Suarez, J., Thomas, K., Schramm, V.L., Tyler, P.C.
Bioorg.Med.Chem.
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