CATH Domain 4yjnA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.200	Phosphorylase Kinase; domain 1
	3.30.200.20	Phosphorylase Kinase; domain 1

Domain Context

CATH Clusters

Superfamily	Phosphorylase Kinase; domain 1
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9BJF5_TOXGO

Toxoplasma gondii

Calmodulin-domain protein kinase 1

PDB Structure

PDB	4YJN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1. Huang, W., Ojo, K.K., Zhang, Z., Rivas, K., Vidadala, R.S., Scheele, S., DeRocher, A.E., Choi, R., Hulverson, M.A., Barrett, L.K., Bruzual, I., Siddaramaiah, L.K., Kerchner, K.M., Kurnick, M.D., Freiberg, G.M., Kempf, D., Hol, W.G., Merritt, E.A., Neckermann, G., de Hostos, E.L., Isoherranen, N., Maly, D.J., Parsons, M., Doggett, J.S., Van Voorhis, W.C., Fan, E. Acs Med.Chem.Lett.