CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.110 | Translation Initiation Factor IF3 |
|
3.30.110.30 | C-terminal domain of ProRS |
Domain Context
CATH Clusters
| Superfamily | C-terminal domain of ProRS |
| Functional Family | Bifunctional glutamate/proline--tRNA ligase |
Enzyme Information
| 6.1.1.15 |
Proline--tRNA ligase.
based on mapping to UniProt Q8I5R7
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
|
UniProtKB Entries (1)
| Q8I5R7 |
SYP_PLAF7
Plasmodium falciparum 3D7
Proline--tRNA ligase
|
PDB Structure
| PDB | 4YDQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis
Structure
|