CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1110 | Calcium-transporting ATPase, cytoplasmic domain N |
|
3.40.1110.10 | Calcium-transporting ATPase, cytoplasmic domain N |
Domain Context
CATH Clusters
| Superfamily | Calcium-transporting ATPase, cytoplasmic domain N |
| Functional Family | Sodium/potassium-transporting ATPase subunit alpha |
Enzyme Information
| 7.2.2.13 |
Na(+)/K(+)-exchanging ATPase.
based on mapping to UniProt Q08DA1
ATP + H(2)O + Na(+)(Side 1) + K(+)(Side 2) = ADP + phosphate + Na(+)(Side 2) + K(+)(Side 1).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed. -!- It is involved in generating the plasma membrane electrical potential. -!- Formerly EC 3.6.1.37 and EC 3.6.3.9.
|
UniProtKB Entries (1)
| G3MWR4 |
G3MWR4_BOVIN
Bos taurus
Sodium/potassium-transporting ATPase subunit beta
|
PDB Structure
| PDB | 4XE5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Isolation, crystallization and crystal structure determination of bovine kidney Na(+),K(+)-ATPase.
Acta Crystallogr.,Sect.F
|