CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Aminopeptidase, subunit E, domain 1
Functional Family M17 leucyl aminopeptidase

Enzyme Information

UniProtKB Entries (1)

Q8IL11
Q8IL11_PLAF7
Plasmodium falciparum 3D7
M17 leucyl aminopeptidase

PDB Structure

PDB 4X2T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17.
Drinkwater, N., Bamert, R.S., Sivaraman, K.K., Paiardini, A., McGowan, S.
Proteins
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