CATH Domain 4w1vA02

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

2.6.1.62

Adenosylmethionine--8-amino-7-oxononanoate transaminase.

based on mapping to UniProt P9WQ80

S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.

-!- S-adenosylhomocysteine can also act as donor.

BIOA_MYCTO

Mycobacterium tuberculosis CDC1551

Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

PDB	4W1V
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis. Park, S.W., Casalena, D.E., Wilson, D.J., Dai, R., Nag, P.P., Liu, F., Boyce, J.P., Bittker, J.A., Schreiber, S.L., Finzel, B.C., Schnappinger, D., Aldrich, C.C. Chem.Biol.