CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.90
Togavirin.
based on mapping to UniProt Q86925
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
-!- Once released, the core protein does not retain catalytic activity. -!- Belongs to peptidase family S3.

UniProtKB Entries (1)

Q86925
POLS_AURAV
Aura virus
Structural polyprotein

PDB Structure

PDB 4UON
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Trans-Protease Activity and Structural Insights Into the Active Form of the Alphavirus Capsid Protease.
Aggarwal, M., Dhindwal, S., Kumar, P., Kuhn, R.J., Tomar, S.
J.Virol.
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