CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome-c3 hydrogenase, C-terminal domain
Functional Family

Enzyme Information

1.12.2.1
Cytochrome-c3 hydrogenase.
based on mapping to UniProt P18187
H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18188
PHNL_DESFR
Desulfovibrio fructosivorans
Periplasmic [NiFe] hydrogenase large subunit

PDB Structure

PDB 4UCX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A threonine stabilizes the NiC and NiR catalytic intermediates of [NiFe]-hydrogenase.
Abou-Hamdan, A., Ceccaldi, P., Lebrette, H., Gutierrez-Sanz, O., Richaud, P., Cournac, L., Guigliarelli, B., De Lacey, A.L., Leger, C., Volbeda, A., Burlat, B., Dementin, S.
J. Biol. Chem.