CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.150 | Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A |
|
2.170.150.20 | Peptide methionine sulfoxide reductase. |
Domain Context
CATH Clusters
| Superfamily | Peptide methionine sulfoxide reductase. |
| Functional Family | Cereblon, isoform CRA_c |
Enzyme Information
UniProtKB Entries (1)
| Q8C7D2 |
CRBN_MOUSE
Mus musculus
Protein cereblon
|
PDB Structure
| PDB | 4TZU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
to be published
|