CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.472 | Cyclin A; domain 1 | |
1.10.472.10 | Cyclin-like |
Domain Context
CATH Clusters
Superfamily | Cyclin-like |
Functional Family |
Enzyme Information
UniProtKB Entries (2)
Q01043 |
CGH2_SHV21
Herpesvirus saimiri (strain 11)
Cyclin homolog
|
Q00534 |
CDK6_HUMAN
Homo sapiens
Cyclin-dependent kinase 6
|
PDB Structure
PDB | 4TTH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.
J.Med.Chem.
|