CATH Classification
Level | CATH Code | Description |
---|---|---|
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.572 | Thymidylate Synthase; Chain A |
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3.30.572.10 | Thymidylate synthase/dCMP hydroxymethylase domain |
Domain Context
CATH Clusters
Superfamily | Thymidylate synthase/dCMP hydroxymethylase domain |
Functional Family |
Enzyme Information
2.1.1.45 |
Thymidylate synthase.
based on mapping to UniProt P00469
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
|
UniProtKB Entries (1)
P00469 |
TYSY_LACCA
Lactobacillus casei
Thymidylate synthase
|
PDB Structure
PDB | 4TMS |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases.
Proteins
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