CATH Domain 4tlrA03

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Superfamily	3.30.70.270
Functional Family	Genome polyprotein

PDB	4TLR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Barnes-Seeman, D., Boiselle, C., Capacci-Daniel, C., Chopra, R., Hoffmaster, K., Jones, C.T., Kato, M., Lin, K., Ma, S., Pan, G., Shu, L., Wang, J., Whiteman, L., Xu, M., Zheng, R., Fu, J. Bioorg.Med.Chem.Lett.