CATH Domain 4rsvA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	obscurin isoform X4

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt Q5VST9

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q5VST9

OBSCN_HUMAN

Homo sapiens

Obscurin

PDB Structure

PDB	4RSV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Arrhythmia and deregulated Ca2+ cycling underlie the development of hypertrophic cardiomyopathy due to mutant giant obscurin Hu, L.Y.R., Ackermann, M.A., Hecker, P.A., Prosser, B.L., King, B., O'Connell, K.A., Asico, L.D., Jose, P.A., Wright, N.T., Oehler, M.C., Berndsen, C.E., Du Pont, K.E., Meyer, L.C., Lederer, W.J., Kontrogianni-Konstantopoulos, A. To be Published