CATH Domain 4rnaA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.1190	Papain-like viral protease, thumb domain

Domain Context

CATH Clusters

Superfamily	1.10.8.1190
Functional Family	ORF1ab polyprotein

Enzyme Information

UniProtKB Entries (1)

K4LC41_9BETC

Human betacoronavirus 2c EMC/2012

ORF1a

PDB Structure

PDB	4RNA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inhibitor Recognition Specificity of MERS-CoV Papain-like Protease May Differ from That of SARS-CoV. Lee, H., Lei, H., Santarsiero, B.D., Gatuz, J.L., Cao, S., Rice, A.J., Patel, K., Szypulinski, M.Z., Ojeda, I., Ghosh, A.K., Johnson, M.E. Acs Chem.Biol.