CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Spermidine N(1)-acetyltransferase

Enzyme Information

2.3.1.57
Diamine N-acetyltransferase.
based on mapping to UniProt P0A951
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

P0A951
ATDA_ECOLI
Escherichia coli K-12
Spermidine N(1)-acetyltransferase

PDB Structure

PDB 4R9M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli.
Filippova, E.V., Weigand, S., Kiryukhina, O., Wolfe, A.J., Anderson, W.F.
Acta Crystallogr D Struct Biol