CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Spermidine N(1)-acetyltransferase

Enzyme Information

2.3.1.57
Diamine N-acetyltransferase.
based on mapping to UniProt Q9KL03
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

Q9KL03
ATDA_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Spermidine N(1)-acetyltransferase

PDB Structure

PDB 4R87
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure.
Filippova, E.V., Kuhn, M.L., Osipiuk, J., Kiryukhina, O., Joachimiak, A., Ballicora, M.A., Anderson, W.F.
J.Mol.Biol.