CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.320.10
Functional Family

Enzyme Information

3.1.12.1
5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
based on mapping to UniProt A3MTK6
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates.
-!- Preference for single-stranded DNA.

UniProtKB Entries (1)

A3MTK6
CAS4_PYRCJ
Pyrobaculum calidifontis JCM 11548
CRISPR-associated exonuclease Cas4

PDB Structure

PDB 4R5Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
Nocek, B., Skarina, T., Lemak, S., Brown, G., Savchenko, A., Joachimiak, A., Yakunin, A.
To be Published