CATH Domain 4qgeB00

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1300	Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b
	1.10.1300.10	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Superfamily	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Functional Family	Phosphodiesterase 9A

3.1.4.35

3',5'-cyclic-GMP phosphodiesterase.

based on mapping to UniProt H2QL32

Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.

PDE9A_PANTR

Pan troglodytes

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

PDB	4QGE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of a Phosphodiesterase 9A Inhibitor as a Potential Hypoglycemic Agent. Shao, Y.X., Huang, M., Cui, W., Feng, L.J., Wu, Y., Cai, Y., Li, Z., Zhu, X., Liu, P., Wan, Y., Ke, H., Luo, H.B. J.Med.Chem.