CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8GZB6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (2)

Q92133
Q92133_XENLA
Xenopus laevis
Histone H3
Q8GZB6
SUVH4_ARATH
Arabidopsis thaliana
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4

PDB Structure

PDB 4QEO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Du, J., Johnson, L.M., Groth, M., Feng, S., Hale, C.J., Li, S., Vashisht, A.A., Gallego-Bartolome, J., Wohlschlegel, J.A., Patel, D.J., Jacobsen, S.E.
Mol.Cell
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